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Dental development in patients with agenesis.
A Lebbe1, M Cadenas de Llano-Pérula1, P Thevissen2
1Department of Oral Health Sciences-Orthodontics, KU Leuven and Dentistry, University Hospitals Leuven, Kapucijnenvoer 7, 3000, Leuven, Belgium.
International Journal of Legal Medicine
|September 19, 2016
Summary
Patients with dental agenesis exhibit delayed tooth development compared to controls. The number of missing teeth correlates with developmental delay, impacting treatment planning and age estimation.
Area of Science:
- Dentistry
- Genetics
- Human Biology
Background:
- Dental agenesis, a common developmental anomaly, is linked to genetic factors.
- These genetic influences may also affect the developmental timing of existing teeth.
Purpose of the Study:
- To investigate if dental development is delayed in individuals with dental agenesis compared to a control group.
- To explore the relationship between the number of missing teeth and the degree of developmental delay.
Main Methods:
- Panoramic radiographs of 1145 patients with dental agenesis and 2032 controls were analyzed.
- Dental development was staged using the Demirjian method, calculating a developmental score (DS).
- Spearman correlation assessed the association between DS and the number of agenetic teeth.
Main Results:
- Patients with dental agenesis showed significantly delayed dental development (p < 0.0001).
- A weak inverse correlation was found between the number of missing teeth and the developmental score in the agenesis group.
- This correlation was significant in females (p < 0.0001) and borderline in males (p = 0.06).
Conclusions:
- Delayed dental development is a characteristic feature in patients with dental agenesis.
- Findings are crucial for effective treatment planning and orthodontic interventions.
- Age estimation methods relying on tooth development require careful consideration of agenesis presence.
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