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Related Experiment Video

Updated: Mar 15, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

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Published on: November 15, 2013

[Not Available].

Li Lei¹, Jinhua Huang¹, Qinghai Zeng¹

¹Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences

|September 20, 2016

Summary

This summary is machine-generated.

The 308 nm excimer laser effectively treats stable vitiligo, with factors like age, disease duration, and lesion location influencing outcomes. This treatment offers a safe option for repigmentation in vitiligo patients.

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Area of Science:

Dermatology
Phototherapy
Vitiligo Treatment

Background:

Vitiligo is a chronic skin condition characterized by depigmentation.
The 308 nm excimer laser is a targeted phototherapy option for vitiligo.
Understanding treatment efficacy and influencing factors is crucial for optimizing patient outcomes.

Purpose of the Study:

To evaluate the efficacy and safety of 308 nm excimer laser for stable vitiligo.
To identify factors influencing treatment response in vitiligo patients.

Main Methods:

An open-label study involving 207 stable vitiligo patients and 1,763 lesions.
Treatment administered using the 308 nm excimer laser.
Analysis of response based on patient demographics, disease characteristics, and lesion attributes.

Main Results:

Significant repigmentation observed, with 31.8% achieving 100% and 36.9% achieving 75%-99% repigmentation.
Higher efficacy noted in younger patients, shorter disease duration (<2 years), and faciocervical lesions.
Patients with poliosis showed a lower response rate compared to those without.

Conclusions:

The 308 nm excimer laser demonstrates significant efficacy and safety in treating stable vitiligo.
Key factors influencing treatment success include patient age, disease duration, lesion location, and presence of poliosis.
Personalized treatment approaches considering these factors may enhance therapeutic outcomes for vitiligo.