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Determining the Phagocytic Activity of Clinical Antibody Samples
Published on: November 30, 2011
Antiphage activity of sera during phage therapy in relation to its outcome
Marzanna Łusiak-Szelachowska1, Maciej Żaczek1, Beata Weber-Dąbrowska1,2
1Laboratory of Bacteriophages, Hirszfeld Institute of Immunology & Experimental Therapy, Polish Academy of Sciences (HIIET PAS), Wrocław, Poland.
Aim:
The aim was to study the association between the phage neutralization of patients' sera and the clinical outcome of phage therapy (PT).
Patients:
About 62 patients with various bacterial infections receiving PT as well as 30 healthy volunteers were studied.
Materials & Methods:
Antiphage activity of sera (AAS) was examined using the phage neutralization test of different types of phages before and during PT in relation to the route of phage administration and correlated with the results of PT.
Results & Conclusion:
The analysis of the association between AAS level and clinical results indicated that the level of AAS is not correlated with the outcome of PT.
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Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause: