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Updated: Mar 14, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
Utility of Laparoscopic Indocyanine Green-Guided Sentinel Node Biopsy in Open Cervical Cancer Surgery
Agnieszka Rychlik1, Silvia Marin, Javier De Santiago
1Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
Objective:
Multiple tracers have been used to improve lymphatic mapping and to reduce the false-negative rate of the sentinel node detection in gynecologic cancers. Nowadays, 99mTc colloids combined with blue-dye technique is the most extended technique. New alternatives such as the fluorescent indocyanine green and near-infrared fluorescent imaging detection have been introduced in lymphatic mapping staging procedures because of its easier visualization compared with the previous tracers.
Methods:
We used the laparoscopic infrared camera for the indocyanine green-guided sentinel node biopsy in a laparotomic radical hysterectomy in a pregnant patient after a cesarean section, with the aim of improving the detection rate of sentinel node biopsy in open surgery.
Results:
The technique was used in the first patient with accurate detection of sentinel node and no complications during the procedure.
Conclusions:
The use of laparoscopic indocyanine green in open surgery may be a useful tool for the detection of sentinel node biopsy.

