Related Experiment Video
Updated: Mar 14, 2026

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
[Emerging infectious agents]
1Service des maladies infectieuses et tropicales, hospices civils de Lyon, GHN, CIRI U1111, hôpital de la Croix-Rousse, université Claude-Bernard Lyon 1, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.
Abstract:
Emergence of many emerging or re-emerging infectious diseases have occurred over the past decade, some of which are major public threat. SARS, MERS-CoV, highly pathogenic avian influenza A(H5N1), Ebola virus disease have raised concerns because of their virulence, their mortality, and/or their modality of transmission, or their impact on maternofoetal transmission (Zika virus). The witness of these emergences have conducted health authorities to have policies and plans and to imagine new organizations for health systems in order to identify any case of highly communicable virulent disease for immediate isolation, and adequate management.
Insights
Emerging infectious diseases like SARS and Ebola pose significant public health threats. Health authorities are developing new strategies for rapid identification and management of highly communicable diseases.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- The past decade has seen a rise in emerging and re-emerging infectious diseases.
- Several diseases, including SARS, MERS-CoV, avian influenza A(H5N1), Ebola virus disease, and Zika virus, have raised global health concerns due to their severity and transmission.
- These outbreaks highlight the need for robust public health systems capable of managing highly communicable and virulent diseases.
Purpose of the Study:
- To underscore the public health threat posed by emerging infectious diseases.
- To emphasize the need for enhanced surveillance and response systems.
- To inform the development of new health system organizations for managing virulent outbreaks.
Main Methods:
- Review of recent emerging and re-emerging infectious disease events.
- Analysis of disease characteristics (virulence, mortality, transmission, maternofoetal transmission).
- Examination of public health authority responses and organizational strategies.
Main Results:
- Significant increase in the occurrence of emerging/re-emerging infectious diseases.
- Identification of key pathogens (SARS, MERS-CoV, H5N1, Ebola, Zika) as major public health concerns.
- Recognition of the need for improved health system organization for rapid case identification, isolation, and management.
Conclusions:
- Emerging infectious diseases represent a substantial and ongoing threat to global public health.
- Effective management requires proactive policies, strategic planning, and adaptable health system organizations.
- Immediate isolation and adequate management protocols are crucial for controlling highly communicable and virulent diseases.
Related Concept Videos
Viral Recombination
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Subviral Agents
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Microorganisms in Medicine and Therapeutics
Chemical Agents for Microbial Control

