Related Experiment Video
Updated: Aug 15, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Borderline spindle cell nevus of the ciliary body as a second primary melanoma--a clinicopathologic case
1Department of Ophthalmology, Beilinson Medical Center, Petah Tiqva, Israel.
Abstract:
We present the case of a 22-year-old woman who underwent surgical excision of a malignant melanoma of the skin three years previously and whom we saw for a pigmented tumor of the iridocorneal angle of her right eye associated with end-stage secondary glaucoma. After the clinical diagnosis of ring melanoma, she underwent enucleation of the eye. The pathologic examination showed a lesion predominantly appearing as a nevus with areas of borderline melanoma formation. The main features of this case were the young age of the patient, the predominant nevoid appearance of this diffuse ciliary body tumor with ring configuration, and the fact that it is a second primary melanoma in such a young patient.
More Related Videos
Related Concept Videos
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

