Related Experiment Video
Updated: Mar 14, 2026

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
Published on: May 10, 2022
Klinefelter syndrome (KS): genetics, clinical phenotype and hypogonadism
M Bonomi1,2, V Rochira3,4, D Pasquali5
1Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Abstract:
Klinefelter Syndrome (KS) is characterized by an extreme heterogeneity in its clinical and genetic presentation. The relationship between clinical phenotype and genetic background has been partially disclosed; nevertheless, physicians are aware that several aspects concerning this issue are far to be fully understood. By improving our knowledge on the role of some genetic aspects as well as on the KS, patients' interindividual differences in terms of health status will result in a better management of this chromosomal disease. The aim of this review is to provide an update on both genetic and clinical phenotype and their interrelationships.
More Related Videos
Related Concept Videos
Sex-linked Disorders
Infertility in Males
X and Y Chromosomes
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
Nondisjunction
Nondisjunction
Nondisjunction

