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A new phenone from the roots of Paeonia suffruticosa Andrews
Liqin Ding1, Qingfei Zuo1, Dandan Li1
1a Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine , Tianjin University of Traditional Chinese Medicine , Tianjin , China.
Natural Product Research
|September 21, 2016
Abstract:
Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time. The inhibitory effects of isolated compounds (1-12) on nitric oxide (NO) production in lipopolysaccharide-activated macrophages were evaluated, and NO production was suppressed significantly by compound 7.