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An Approach to the Commercial Production of Highly Active Pharmaceutical Ingredients
Andreas Beyeler1, Roland Wilhelm2, Bernd Brodbeck2
1F. Hoffmann-La Roche AG Grenzacherstrasse 124 CH-4058 Basel, Switzeerland. andreas.beyeler@roche.com.
Abstract:
To meet the requirements for production of highly active pharmaceutical ingredients (API) new approaches and technical solutions are required. Prior to the design and construction of a new multipurpose manufacturing facility, a process study was performed to clarify the future needs. During the planning phase, concepts were defined and elaborated to meet production, cleaning, health and safety standards. The ideas were taken into account and a small-scale manufacturing facility was designed and realized accordingly.
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