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[Urinary calculi in children. Etiologic survey]
Insights
Urinary calculi in children often stem from metabolic issues like hyperoxaluria, hypercalciuria, and cystinuria, or urinary tract infections. A proposed metabolic evaluation protocol aids in identifying these causes.
Area of Science:
- Pediatric Nephrology
- Urology
- Medical Biochemistry
Context:
- Urinary calculi (kidney stones) present a significant health challenge in pediatric populations.
- Identifying the underlying etiology of pediatric urolithiasis is crucial for effective management and prevention.
Purpose:
- To investigate the prevalence of metabolic and infectious causes of urinary calculi in a cohort of 33 children.
- To propose a standardized protocol for the metabolic evaluation of pediatric patients with urolithiasis.
Summary:
- Metabolic abnormalities were identified in 12 children, including hyperoxaluria (4), hypercalciuria (6), and cystinuria (2).
- Urinary tract infections were associated with lithiasis in 14 children.
- In 7 children, no identifiable cause for urinary calculi was found.
Impact:
- This study highlights the importance of comprehensive metabolic screening in children with kidney stones.
- The proposed evaluation protocol can guide clinicians in diagnosing and managing pediatric urolithiasis, potentially reducing recurrence rates.
Abstract:
Thirty-three children with urinary calculi were studied. In 12, a metabolic cause of calculi was identified (4 hyperoxaluria, 6 hypercalciuria, 2 cystinuria). In 14 children, lithiasis was associated with a urinary tract infection. No identifiable cause could be found in 7 children. A protocol for metabolic evaluation is proposed.