Related Experiment Video
Updated: Aug 12, 2026

Steps for the Autologous Ex vivo Perfused Porcine Liver-kidney Experiment
Published on: December 18, 2013
Perfusion of uremic blood ultrafiltrate on uncoated charcoal
L Politi1, N Cerulli, A R D'Angelo
1Dipartimento di Scienze e Tecnologie Biomediche, Università de L'Aquila, Rome, Italy.
Abstract:
A granular uncoated charcoal removes from uremic blood ultrafiltrates many chemical species that are not removed by dialysis. Charcoal treatment dramatically improves the general condition of the patients and normalizes their blood pressure. To obtain a rapid depuration, the initial treatment should be intensive (at least 16 daily treatments) and the effects prolonged over time by once-a-week charcoal treatment between two standard hemodialyses. Biogel P2 chromatography documents well all the events of a depurative treatment that cannot be monitored by hematochemical analyses.
Related Concept Videos
Filtration and Urine Formation
Drug Dosing in Renal Diseases: Measurement of Glomerular Filtration Rate
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy

