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Total mesopancreas excision for pancreatic head cancer: analysis of 120 cases
Wenguang Wu1, Xu'an Wang1, Xiangsong Wu1
1Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China; Institute of Biliary Tract Disease, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Objective:
To evaluate the feasibility and safety of total mesopancreas excision (TMpE) in the treatment of pancreatic head cancer.
Methods:
The clinical and pathological data of 120 patients with pancreatic head cancer who had undergone TMpE in our center from May 2010 to January 2014 were retrospectively analyzed.
Results:
The mean operative time was (275.0±50.2) min and the average intra-operative blood loss was (390.0±160.5) mL. Post-operative complications were reported in 45 patients, while no peri-operative death was noted. The specimen margins were measured in three dimensions, and 86 patients (71.6%) achieved R0 resection.
Conclusions:
TMpE is safe and feasible for pancreatic head cancer and is particularly helpful to increase the R0 resection rate.
Insights
Total mesopancreas excision (TMpE) is a safe and feasible surgical approach for pancreatic head cancer. This technique effectively increases the rate of R0 resection, improving patient outcomes.
Area of Science:
- Surgical Oncology
- Gastrointestinal Surgery
Background:
- Pancreatic head cancer presents significant treatment challenges.
- Complete tumor removal is crucial for improving patient survival rates.
Purpose of the Study:
- To assess the feasibility and safety of total mesopancreas excision (TMpE) for pancreatic head cancer.
- To evaluate the impact of TMpE on achieving R0 resection rates.
Main Methods:
- Retrospective analysis of clinical and pathological data.
- 120 patients with pancreatic head cancer underwent TMpE between May 2010 and January 2014.
Main Results:
- Mean operative time was 275.0±50.2 minutes; average blood loss was 390.0±160.5 mL.
- 45 patients experienced post-operative complications; no peri-operative deaths occurred.
- 86 patients (71.6%) achieved R0 resection, indicating complete tumor removal.
Conclusions:
- TMpE is a safe and feasible surgical option for pancreatic head cancer.
- TMpE significantly enhances the likelihood of achieving R0 resection.
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