Strong Association Between Endometriosis and Symptomatic Leiomyomas
Camran Nezhat1, Anjie Li1, Sozdar Abed2
1Center for Special Minimally Invasive and Robotic Surgery, Palo Alto, California, USA.
JSLS : Journal of the Society of Laparoendoscopic Surgeons
|September 21, 2016
Summary
In women with symptomatic leiomyoma (fibroids), 87.1% also had endometriosis. This highlights the importance of diagnosing and treating both conditions simultaneously to manage pelvic pain and fertility issues effectively.
Area of Science:
- Gynecology
- Reproductive Medicine
- Surgical Pathology
Background:
- The relationship between uterine leiomyoma (fibroids) and endometriosis is not well understood.
- Both conditions can cause significant pelvic pain and impact fertility.
- This study aimed to determine the rate of endometriosis in women presenting with symptomatic leiomyoma.
Purpose of the Study:
- To assess the prevalence of endometriosis in women diagnosed with symptomatic leiomyoma.
- To evaluate the necessity of simultaneous diagnosis and treatment for both conditions.
Main Methods:
- Retrospective review of medical records of 244 patients treated for symptomatic leiomyoma.
- Analysis of 208 patients who underwent surgical treatment (myomectomy or hysterectomy).
- Exclusion of 36 patients treated with medical therapy.
Main Results:
- Of 208 surgically treated patients, 181 (87.1%) had both leiomyoma and endometriosis.
- Patients with both conditions were younger and more likely to report pelvic pain and nulliparity.
- Adenomyosis was present in 9 of the 27 patients with leiomyoma alone.
Conclusions:
- A high rate of endometriosis coexistence (87.1%) was observed in women with symptomatic leiomyoma.
- Simultaneous diagnosis and treatment are crucial for optimal management of pain and fertility.
- Physicians should actively screen for endometriosis during myomectomy or hysterectomy to prevent suboptimal outcomes and reoperation.
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