Related Experiment Video
Updated: Mar 14, 2026
Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
Optic nerve astrocytoma in a dog
Orr Rozov1, Pablo E Piñeyro2, Kurt L Zimmerman1
1Department of Biomedical Sciences and Pathobiology Virginia-Maryland College of Veterinary Medicine Virginia Tech Blacksburg Virginia 24061-0442 USA.
Optic nerve astrocytomas are rare intracranial neoplasms in dogs. Consider this diagnosis in dogs with vision loss and specific ocular findings.
Area of Science:
- Veterinary Neurology
- Ophthalmology
- Canine Oncology
Background:
- Intracranial astrocytomas are uncommon canine brain tumors.
- Optic nerve astrocytomas represent a rare subset of these neoplasms.
Observation:
- Canine patients may present with vision loss, retinal detachment, or ocular masses.
- Histopathology reveals infiltrative glial cells, often fusiform to polygonal in shape.
- Glomeruloid vascular proliferation may be associated with these tumors.
Findings:
- Optic nerve astrocytoma should be a differential diagnosis for canine vision impairment.
- Characteristic histopathologic features aid in diagnosis.
Implications:
- Early consideration of optic nerve astrocytoma can improve diagnostic timelines.
- Accurate diagnosis is crucial for appropriate patient management and prognosis in veterinary oncology.
More Related Videos
12:06Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
09:52An Orthotopic Glioblastoma Mouse Model Maintaining Brain Parenchymal Physical Constraints and Suitable for Intravital Two-photon Microscopy
Published on: April 21, 2014