Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

Area of Science:

• Nanoscience and Nanotechnology
• Biomedical Applications
• Nanomedicine

Background:

• Nanoscience and nanotechnology have revolutionized disease diagnosis, treatment, and prevention.
• Silver nanoparticles (AgNPs) are key metallic nanomaterials with extensive biomedical applications.
• AgNPs are particularly significant in nanomedicine for their potential in cancer diagnosis and therapy.

Purpose of the Study:

• To review the synthesis, properties, and characterization of silver nanoparticles (AgNPs).
• To extensively discuss the multifunctional bio-applications of AgNPs, focusing on their role in cancer therapy.
• To explore the mechanisms of anti-cancer activity, therapeutic approaches, and future perspectives of AgNPs.

Main Methods:

• Discussion of physical, chemical, and biological synthesis methods for AgNPs.
• Review of characterization techniques for assessing AgNP properties.
• Comprehensive analysis of literature on AgNP bio-applications and anti-cancer mechanisms.

Main Results:

• AgNPs exhibit diverse biological activities, including antibacterial, antifungal, antiviral, anti-inflammatory, and anti-angiogenic properties.
• AgNPs demonstrate significant potential as anti-cancer agents, with various mechanisms of action explored.
• The review covers synthesis, properties, characterization, and multifaceted applications of AgNPs in nanomedicine.

Conclusions:

• Silver nanoparticles (AgNPs) are versatile nanomaterials with broad therapeutic potential, particularly in oncology.
• Further research into AgNPs is crucial for overcoming challenges and realizing their full potential in cancer therapy.
• The future of AgNPs in nanomedicine is promising, with ongoing advancements in synthesis and application.