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Female sexual dysfunction post radical cystectomy and urinary diversion.

M H Zahran1, O Fahmy2,3, A S El-Hefnawy1

  • 1a Urology and Nephrology Center , Mansoura University , Egypt.

Climacteric : the Journal of the International Menopause Society
|September 21, 2016
PubMed
Summary

Radical cystectomy and urinary diversion significantly impact female sexual function, with loss of sexual desire and orgasm disorders being most common. Nerve-sparing techniques may reduce sexual dysfunction incidence.

Keywords:
Radical cystectomyfemale cystectomyquality of lifesexual dysfunctionurinary diversionwomen

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Area of Science:

  • Urology
  • Oncology
  • Sexual Medicine

Background:

  • Radical cystectomy (RC) and urinary diversion (UD) are standard treatments for bladder cancer.
  • Female sexual function (FSF) is a crucial component of health-related quality of life (HRQoL) post-RC.
  • Limited data exists on the specific impact of RC and UD on FSF.

Purpose of the Study:

  • To systematically review the literature on the impact of RC and UD on FSF.
  • To identify common female sexual dysfunctions (FSD) post-RC.
  • To explore factors associated with FSD and its recovery.

Main Methods:

  • A systematic literature search was performed using Medline (1980-2016) adhering to PRISMA guidelines.
  • Included studies focused on FSF assessment after RC and UD.
  • Data extraction and critical analysis of 11 eligible studies involving 361 women.

Main Results:

  • Loss of sexual desire (49%) and orgasm disorders (39%) were the most prevalent FSDs.
  • Dyspareunia (25%) and vaginal lubrication disorders (9.5%) were also reported.
  • Incidence of FSD was significantly lower with genital-/nerve-sparing RC (10%) versus conventional RC (59%).

Conclusions:

  • FSF is a vital aspect of HRQoL after RC and UD.
  • Current literature is insufficient to provide comprehensive guidance for surgeons and patients.
  • Further research is needed to better understand and manage FSD post-RC.