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Somatically expressed germ-granule components, PGL-1 and PGL-3, repress programmed cell death in C. elegans

Mohammad Al-Amin1, Hyemin Min1, Yhong-Hee Shim1

  • 1Department of Bioscience and Biotechnology, Konkuk University, Seoul, Republic of Korea.

Scientific Reports
|September 22, 2016
PubMed
Summary

Germ-granule proteins PGL-1 and PGL-3 negatively regulate apoptosis in both germ and somatic cells of C. elegans. Loss of these proteins increases germline cell death, while their ectopic expression reduces somatic cell death.

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