Low-level laser therapy: Case-control study in dogs with sterile pyogranulomatous pododermatitis

Area of Science:

• Veterinary Dermatology
• Photomedicine
• Biotechnology

Background:

• Sterile pyogranulomatous pododermatitis is a challenging canine skin condition.
• Low-level laser therapy (LLLT) utilizes photobiostimulation for anti-inflammatory and tissue healing effects.

Purpose of the Study:

• To pilot the efficacy of LLLT in treating sterile pyogranulomatous pododermatitis in dogs.
• To compare LLLT with conventional hydrocortisone aceponate spray.

Main Methods:

• A pilot study involving five dogs with sterile pyogranulomatous pododermatitis.
• Lesions were treated daily for 5 days with either a gallium aluminum arsenide-laser or hydrocortisone aceponate spray.
• Clinical scoring was performed at multiple time points: D0, D4, D20, and D65.

Main Results:

• LLLT-treated lesions showed statistically significant improvement by D4 and D20 compared to controls.
• The LLLT group exhibited significant improvement over time (D0, D4, D20).
• Over 50% of LLLT-treated lesions showed no recurrence at D65, with no adverse reactions reported.

Conclusions:

• LLLT shows positive preliminary results for sterile pyogranulomatous pododermatitis in dogs.
• Further studies are warranted to confirm LLLT's therapeutic value in this condition.
• LLLT presents a potentially safe and effective treatment modality.