Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

4.6K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
4.6K
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

339
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
339
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

93
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
93
Pharmacovigilance01:19

Pharmacovigilance

1.9K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K
Drug Administration and Therapy Phases: Overview01:26

Drug Administration and Therapy Phases: Overview

1.6K
Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
1.6K
The Placebo Effect01:54

The Placebo Effect

7.0K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
7.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses.

Antimicrobial agents and chemotherapy·2012
Same author

Development of CMX001 for the Treatment of Poxvirus Infections.

Viruses·2011
Same author

Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.

Viruses·2011
Same author

Efficacy of CMX001 as a prophylactic and presymptomatic antiviral agent in New Zealand white rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.

Viruses·2011
Same author

Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies.

Virology·2008
Same author

Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001.

Antiviral therapy·2008

Related Experiment Video

Updated: Mar 14, 2026

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
08:56

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Published on: April 7, 2023

1.5K

Mixed feelings over pill warnings.

Alice Robertson1

  • 1Edinburgh.

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|September 23, 2016
PubMed
Summary
This summary is machine-generated.

Government announcements about contraceptive pills increasing blood clot risk have caused confusion. Further research is needed to clarify the actual risks associated with these hormonal contraceptives.

More Related Videos

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.7K
Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K

Related Experiment Videos

Last Updated: Mar 14, 2026

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
08:56

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Published on: April 7, 2023

1.5K
Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.7K
Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K

Area of Science:

  • Pharmacology
  • Public Health
  • Epidemiology

Background:

  • Recent government announcements have raised public concern regarding specific contraceptive pill brands.
  • The purported link between certain oral contraceptives and an increased risk of blood clots has generated confusion.

Purpose of the Study:

  • To critically evaluate the scientific basis of claims linking seven contraceptive pill brands to increased blood clot risk.
  • To provide a clear, evidence-based perspective on the association between oral contraceptives and thromboembolic events.

Main Methods:

  • Review of existing epidemiological studies and clinical trial data.
  • Analysis of pharmacovigilance reports and regulatory agency assessments.
  • Assessment of the methodologies and conclusions of prior research.

Main Results:

  • The evidence linking specific contraceptive pill brands to a significantly increased risk of blood clots is often presented without adequate context.
  • The absolute risk increase for most users remains low, though variations exist between different progestogen types.
  • Conflicting interpretations of data contribute to public and medical professional confusion.

Conclusions:

  • Clearer communication is needed regarding the nuanced risks of oral contraceptives.
  • Further research should focus on identifying specific risk factors and user subgroups.
  • Public health messaging should be based on robust scientific consensus to avoid unnecessary alarm.