Related Experiment Video
Updated: Mar 14, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
Published on: September 7, 2022
Overview of Total Knee Arthroplasty and Modern Pain Control Strategies
Lacey Giambelluca Lavie1, M Patricia Fox2, Vinod Dasa3
1LSUHSC School of Medicine, 433 Bolivar Street, New Orleans, LA, 70112, USA.
Abstract:
Perioperative pain management of total knee arthroplasty (TKA) remains a challenge for physicians and anesthesiologists. Reducing postoperative pain is an essential component of patient satisfaction, functional outcomes, and hospital length of stay. Multimodal pain management regimens have been demonstrated to be superior to monotherapy in achieving adequate pain control, as well as an effective method of limiting side effects of analgesics. In the present investigation, we present literature published over the last year relating to new advancements in perioperative pain management for TKA. While it is widely accepted that methods including peripheral nerve blocks and local anesthetic injections are essential to pain protocols, there is still conflicting evidence over what modalities provide superior relief. The incorporation of cryoneurolysis preoperatively is a new modality which has been incorporated and has been shown to improve pain control in patients undergoing TKA.
Related Concept Videos
Analgesia and Pain Management
Peripheral Artery Disease V: Postoperative Nursing Management
Opioid Analgesics: Synthetic and Semisynthetic Opioids

