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Hip structure analysis by DXA of teriparatide treatment: A 24-month follow-up clinical study
Takeshi Mochizuki1, Koichiro Yano2, Katsunori Ikari2
1Department of Rheumatology and Orthopaedic Surgery, Kamagaya General Hospital, Chiba, Japan.
Objective:
The objective of this study was to perform a hip structure analysis (HSA) of teriparatide (TPTD) treatment in women with postmenopausal osteoporosis.
Methods:
The study included 96 patients with postmenopausal osteoporosis and received 20 μg TPTD daily. HSA was performed by dual-energy X-ray absorptiometry.
Results:
The percent changes from baseline for the cross-sectional moment of inertia, section modulus, buckling ratio, and femoral strength index based on HSA results were 9.8% (p < 0.01), 10.7%, 3.3%, and 14.9% (p < 0.01), respectively, at 24 months.
Conclusion:
Based on the HSA results obtained with DXA, TPTD was effective for hip structures.
