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Neurogenic Bladder Repair Using Autologous Mesenchymal Stem Cells
Pradeep V Mahajan1, Swetha Subramanian1, Amit Danke1
1StemRx Bioscience Solutions Pvt. Ltd., Navi Mumbai, India.
Case Reports in Urology
|September 23, 2016
Summary
Neurogenic bladder, a urinary dysfunction, can result from neurological issues. Autologous cellular therapy using mesenchymal stem cells shows promise in treating this condition, potentially improving bladder function.
Area of Science:
- Urology
- Neurology
- Regenerative Medicine
Background:
- The urinary bladder stores and expels urine, regulated by nervous systems.
- Neurogenic bladder arises from neurological dysfunction due to trauma, disease, or injury.
- Diabetes mellitus with neuropathy can contribute to bladder dysfunction.
Purpose of the Study:
- To report a case of neurogenic bladder following laminectomy and diabetes.
- To evaluate the efficacy of autologous cellular therapy in treating neurogenic bladder.
- To highlight the potential of mesenchymal stem cells in restoring bladder function.
Main Methods:
- A case study of a patient with neurogenic bladder was presented.
- Treatment involved autologous cellular therapy.
- Mesenchymal stem cells were utilized for their differentiation and paracrine effects.
Main Results:
- The patient's neurogenic bladder was treated with autologous cellular therapy.
- Mesenchymal stem cells demonstrated differentiation potential.
- Paracrine effects of stem cells on bladder function were observed.
Conclusions:
- Autologous cellular therapy is a potential treatment for neurogenic bladder.
- Mesenchymal stem cells offer therapeutic benefits for bladder dysfunction.
- Further research into stem cell therapy for neurogenic bladder is warranted.
