Related Experiment Video
Updated: Mar 14, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Comparative Evaluation of Longevity of Fluoride Release From three Different Fluoride Varnishes - An Invitro Study
Shruti Girish Virupaxi1, N M Roshan2, P Poornima3
1Senior Lecturer, Department of Pediatric Dentistry, Maratha Mandals NGH Institute of Dental Sciences , Belagavi, Karnataka, India .
Introduction:
Fluoride varnishes play a pivotal role in inhibition of dental caries by increasing remineralization.
Aim:
To determine the longevity of fluoride release from 3 different fluoride varnishes over a period of time through salivary fluoride estimation.
Materials And Methods:
Twenty four extracted human deciduous anterior teeth were divided into four groups, i.e., ClinproTM XT, Flouritop SR, Flourprotector and Control group. Fluoride varnishes were applied on 3mm x 3mm window on labial surface of the teeth and then the teeth were immersed and stored in artificial saliva. The concentration of fluoride in ppm was measured after 1 week, 1 month, 3 months and 6 months. Fluoride release at each time interval for different groups was statistically analyzed using ANOVA and Post Hoc Tukey's test.
Results:
Although all the fluoride varnishes released fluoride, with greatest release observed during 1(st) week by Fluoritop SR (66.92±16.30ppm), ClinproTM XT Varnish released consistently and substantially more fluoride than Fluoritop SR and Fluorprotector during 6 months analysis (p<0.05). Fluorprotector showed the lowest rate of F release among all the groups compared.
Conclusion:
Over a period of 6 months ClinproTM XT Varnish released consistently and substantially more fluoride than other tested products.

