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Updated: Mar 14, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Two New Clerodane Diterpenes from Tinospora sagittata
Guanhua Li1, Wenbing Ding2,3, Fanghao Wan4,5
1College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. liguanhua@hunau.edu.cn.
Abstract:
Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems of Tinospora sagittata (Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5). The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound 1 was assigned by experimental and calculated ECD spectra. The cytotoxicity and α-glucosidase inhibitory activities of isolated compounds were evaluated in vitro.
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