Related Experiment Video

Updated: Mar 14, 2026

Micropatterning and Assembly of 3D Microvessels
13:05

Micropatterning and Assembly of 3D Microvessels

Published on: September 9, 2016

12.5K

Correction: HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human

Tessa D Nauta, Monique C A Duyndam, Ester M Weijers

    Plos One
    |September 23, 2016
    PubMed

    Abstract:

    [This corrects the article DOI: 10.1371/journal.pone.0160700.].

    More Related Videos

    Induction of Hypoxia in Living Frog and Zebrafish Embryos
    08:01

    Induction of Hypoxia in Living Frog and Zebrafish Embryos

    Published on: June 26, 2017

    10.2K
    2.5D Model for Ex Vivo Mechanical Characterization of Sprouting Angiogenesis in Living Tissue
    10:00

    2.5D Model for Ex Vivo Mechanical Characterization of Sprouting Angiogenesis in Living Tissue

    Published on: February 28, 2025

    920

    Related Experiment Videos

    Last Updated: Mar 14, 2026

    Micropatterning and Assembly of 3D Microvessels
    13:05

    Micropatterning and Assembly of 3D Microvessels

    Published on: September 9, 2016

    12.5K
    Induction of Hypoxia in Living Frog and Zebrafish Embryos
    08:01

    Induction of Hypoxia in Living Frog and Zebrafish Embryos

    Published on: June 26, 2017

    10.2K
    2.5D Model for Ex Vivo Mechanical Characterization of Sprouting Angiogenesis in Living Tissue
    10:00

    2.5D Model for Ex Vivo Mechanical Characterization of Sprouting Angiogenesis in Living Tissue

    Published on: February 28, 2025

    920

    Related Concept Videos

    Regulation of Angiogenesis and Blood Supply01:24

    Regulation of Angiogenesis and Blood Supply

    3.9K
    Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
    3.9K

    Articles linked to this work by shared authors, journal, and citation graph.

    Endothelial RhoGEF Trio is involved in angiogenesis.

    Vascular biology (Bristol, England)·2026

    Regulation of Pleiotrophin and PTPRZ1 Expression by Hypoxia to Restrict Hypoxia-Induced Cell Migration.

    Cancers·2025

    Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation.

    Angiogenesis·2021

    Empagliflozin restores chronic kidney disease-induced impairment of endothelial regulation of cardiomyocyte relaxation and contraction.

    Kidney international·2020

    Skin substitutes are more potent than dermal or epidermal substitutes in stimulating endothelial cell sprouting.

    BMC biomedical engineering·2020

    Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity.

    Journal of cell science·2020

    Transient Activation of Developmental Cytoskeletal Remodeling Programs After Traumatic Brain Injury: A Multiple-Reactivation Model of Neurodegeneration.

    Cureus·2026

    Trifluoroacetate mediated reduction of atherosclerosis in mice.

    Nature communications·2026

    Ultrafast Micrometric Laser Structuring of Polymer Surfaces for Highly Organized Skeletal Muscle Tissue Modeling.

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

    Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli.

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

    Optimization of PEI-mediated transient transfection for antibody production in Expi293F cells by iron ion supplementation.

    Biochemistry and biophysics reports·2026

    GJA1-mediated mitochondrial transfer from adipose-derived stem cells underpins the enhanced therapeutic efficacy of tetramethylpyrazine on wound healing.

    Cytotechnology·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us