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Updated: Mar 14, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Cytology of Pericardial Effusion due to Malignancy
Background:
Malignant pericardial effusion occurs in one tenth of all cancers. It is a very serious disorder that is mainly a secondary process due to metastasis because primary neoplasms of the pericardium such as mesotheliomas, sarcomas being exceedingly rare [corrected]. Pericardial effusion specimens are uncommon and to the best of our knowledge the current study is the largest systematic evaluation of pericardial fluid cytology performed to date.
Material And Methods:
Pericardial effusion specimens from 145 patients collected over a 25 [corrected] year period were studied by cytology [corrected]. The minimum pericardial fluid volume used for adequate cytologic diagnosis in these patients was more than 60 mL.
Results:
Cytological diagnosis revealed malignant pericardial exudates in 100% of the studied patients [corrected].
Conclusions:
Cytology provides an immediate and accurate means of diagnosis. Immunocytology is very important in the diagnostic evaluation.
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