Related Experiment Video

Updated: Mar 14, 2026

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
15:29

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Published on: August 5, 2016

8.7K

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

Kayode K Ojo, Ranae M Ranade, Zhongsheng Zhang

    Plos One
    |September 23, 2016
    PubMed
    Summary

    This study corrects a previously published article DOI. The correction ensures accurate citation and retrieval of scientific research for the scientific community.

    More Related Videos

    Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems06:18

    Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems

    Published on: April 26, 2019

    6.5K
    Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues12:07

    Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

    Published on: November 22, 2014

    14.5K

    Related Concept Videos

    Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase01:11

    Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

    Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
    63
    tRNA Activation02:26

    tRNA Activation

    Aminoacyl-tRNA synthetases are present in both eukaryotes and bacteria. Though eukaryotes have 20 different aminoacyl-tRNA synthetases to couple to 20 amino acids, many bacteria do not have genes for all of these aminoacyl-tRNA synthetases. Despite this, they still use all 20 amino acids to synthesize their proteins. For instance, some bacteria do not have the gene encoding the enzyme that couples glutamine with its partner tRNA. In these organisms, one enzyme adds glutamic acid to all of the...
    23.7K
    Initiation of Translation02:33

    Initiation of Translation

    Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
    First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
    39.9K