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Related Experiment Video

Updated: Mar 14, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
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Follow-up after surgery for hemorrhagic AMD.

D Garcia1, L Mahieu2, G Soubrane3

  • 1Ophthalmology department, centre hospitalier de Bigorre, boulevard Maréchal-de-Lattre-de-Tassigny, 65000 Tarbes, France; Retina unit, ophthalmology department, hôpital Pierre-Paul-Riquet, CHU de Toulouse, place du Docteur-Baylac, TSA 40031, 31059 Toulouse cedex 9, France.

Journal Francais D'Ophtalmologie
|September 24, 2016
PubMed
Summary
This summary is machine-generated.

Monthly follow-up after macular hematoma surgery in exudative age-related macular degeneration (AMD) is recommended. More frequent monitoring preserves postoperative visual acuity compared to less frequent follow-up schedules.

Keywords:
Activateur tissulaire du plasminogèneAnti-VEGFDMLA exsudativeFollow-upInjection intravitréenneIntravitreal injectionSuiviTissue plasminogen activatorVitrectomieVitrectomyWet macular degeneration

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Age-Related Macular Degeneration (AMD)

Background:

  • Long-term functional outcomes after macular hematoma (MH) surgery in exudative AMD are often suboptimal.
  • Subretinal macular hemorrhage (SMH) management in AMD requires careful monitoring.

Purpose of the Study:

  • To compare visual outcomes between monthly and bimestrial postoperative follow-up schedules in patients who underwent surgery for SMH associated with exudative AMD.
  • To determine the optimal follow-up frequency for preserving visual acuity after SMH surgery.

Main Methods:

  • Retrospective, interventional case series of 21 eyes with SMH associated with exudative AMD.
  • Patients were divided into two groups based on postoperative visit frequency: ≥11 visits (monthly) or 6-10 visits (bimestrial).
  • All patients underwent vitrectomy, subretinal recombinant tissue plasminogen activator injection, fluid-gas exchange, and anti-VEGF intravitreal injections (IVT).

Main Results:

  • The monthly follow-up group (≥11 visits) demonstrated statistically significant greater visual acuity (VA) changes (logMAR -0.29±0.44) compared to the bimestrial group (logMAR 0.42±0.73) at 1-year postoperative.
  • Patients in the monthly follow-up group received more anti-VEGF IVTs for exudative recurrences (ER).

Conclusions:

  • Monthly postoperative follow-up, including monitoring between intravitreal injection (IVT) series, is highly recommended.
  • This intensive monitoring strategy helps preserve postoperative visual acuity in patients undergoing surgery for SMH associated with AMD.