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Updated: Mar 14, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
[CONGENITAL DEFICIENCY OF COAGULATION FACTOR V]
M Kvezereli-Kopadze1, A Kvezereli-Kopadze1, M Chikovani1
1Tbilisi State Medical University, G. Zhvania Pediatric Academic Clinic, Tbilisi, Georgia.
Abstract:
The study was designed to investigate the 5 year old girl with rare bleeding disorder -deficiency of coagulation factor V. The diagnosis was based on detail family history, physical examination and para-clinical data analyses. The age of patient, purpura, this has been detected from early age, positive family history, non-controlled, longtime bleeding, inadequate trauma of the tongue, which did not resolve after surgery, strong hypocoagulation, which was slightly improved, after several plasma transfusions. This allowed us to suggest the existence of the congenital coagulopathy, which was confirmed by the investigation of coagulation factors - particularly the deficiency of factor V was detected.
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