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Practice Bulletin No. 172 Summary: Premature Rupture of Membranes

    Obstetrics and Gynecology
    |September 24, 2016
    PubMed

    Insights

    Preterm premature rupture of membranes (PROM) affects 3% of US pregnancies. Management guidelines are presented, balancing delivery risks against expectant management, informed by research and expert opinion.

    Area of Science:

    • Obstetrics and Gynecology
    • Perinatal Medicine

    Background:

    • Preterm delivery impacts 12% of US births, causing significant perinatal morbidity and mortality.
    • Preterm premature rupture of membranes (PROM) complicates 3% of US pregnancies.
    • Optimal clinical management for PROM remains debated.

    Purpose of the Study:

    • To review current understanding of preterm premature rupture of membranes (PROM).
    • To provide evidence-based and consensus-driven management guidelines for PROM.
    • To inform clinical decision-making regarding delivery versus expectant management.

    Main Methods:

    • Literature review of outcome-based research on PROM management.
    • Incorporation of expert opinion and consensus for guideline development.
    • Analysis of risks associated with delivery versus expectant management.

    Main Results:

    • Guidelines address clinical assessment and treatment strategies for PROM.
    • Management decisions weigh risks of delivery against complications of expectant management (infection, abruptio placentae, cord accident).
    • Recommendations are based on available outcome data and expert consensus.

    Conclusions:

    • Standardized guidelines are needed for PROM management.
    • Balancing maternal and fetal risks is crucial in PROM cases.
    • Further outcome-based research can refine PROM management protocols.

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