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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

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Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
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Fighter Pilot with Recurrent Central Serous Chorioretinopathy.

Kevin C Dietrich1

  • 1Eglin AFB, FL, USA.

Aerospace Medicine and Human Performance
|September 24, 2016
PubMed
Summary

Central serous chorioretinopathy (CSC) can disqualify pilots due to vision demands. This case highlights treatment challenges and the need for further research on G-force effects in aviators with CSC.

Area of Science:

  • Ophthalmology
  • Aerospace Medicine

Background:

  • Central serous chorioretinopathy (CSC) is typically self-limiting but can recur, causing permanent visual defects.
  • Aviation necessitates perfect vision, making pilots with CSC ineligible for flight duties.
  • Recurrent CSC poses significant career risks for pilots.

Observation:

  • A fighter pilot with 1260 flight hours developed CSC in his right eye.
  • Multiple treatments including watchful waiting, micropulse laser, and rifampin were administered over three years.
  • Rifampin showed initial response but was discontinued due to elevated liver enzymes; micropulse laser failed to resolve subretinal fluid.

Findings:

  • The pilot developed chronic CSC despite various treatments.
  • The condition led to career termination due to visual concerns and potential G-force impact.

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  • No studies currently address the effect of G-force on subretinal fluid in CSC patients.

    • Implications:

    • Persistent CSC in pilots raises safety concerns in aviation.
    • Mitigation strategies may involve multi-crew aircraft operations.
    • Further research is needed on G-force effects on CSC prognosis in aviators.