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Related Concept Videos

Reporter Genes02:11

Reporter Genes

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific...
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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Receptor tyrosine kinases or RTKs are membrane-bound receptors that phosphorylate specific tyrosine on protein substrates. RTKs regulate cellular growth, differentiation, survival, and migration. They contain an extracellular ligand binding domain, a transmembrane domain, and a cytosolic tail with intrinsic kinase activity. Several extracellular signaling molecules activate RTKs in one or more ways and relay the signal downstream. Ligands such as platelet-derived growth factor (PDGF) or...
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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM
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Research for a star?

Simon Rundeli1

  • 1At the Middlesex Hospital Intensive Therapy Unit.

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|September 25, 2016
PubMed
Summary

Nursing research is essential for professional advancement. Embracing scientific study elevates the nursing profession and validates its critical role in healthcare.

Area of Science:

  • Nursing Science
  • Healthcare Research

Background:

  • The Briggs Committee recommended nursing become a research-based profession.
  • There is a recognized need for scientific justification within nursing practice.

Purpose of the Study:

  • To explore the foundational role of research in nursing.
  • To examine how scientific study impacts professional status.

Main Methods:

  • Literature review on nursing research mandates.
  • Analysis of historical calls for evidence-based practice.

Main Results:

  • Nursing research is increasingly accepted as fundamental.
  • Scientific inquiry is a key strategy for professional validation.

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Conclusions:

  • Research is integral to modern nursing practice.
  • Elevating nursing status is achieved through rigorous scientific investigation.