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Calculating drug dosage and accumulation in multiple-dose regimens is crucial for achieving therapeutic efficacy while avoiding toxicity. This involves determining the plasma drug concentrations over time to optimize dosing schedules. The principle of superposition is fundamental in this process, allowing for the prediction of drug concentration in plasma following multiple doses based on single-dose data.The principle of superposition asserts that the plasma concentration-time curves from...
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Dosage Regimen: Individualization01:24

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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[Patient's preferences for repeat prescriptions in general practice].

Julie Siproudhis1, Anthony Chapron2, Emmanuel Allory2

  • 1Département de médecine générale, université de Rennes 1, 2, avenue du Pr-Léon-Bernard, 35043 Rennes cedex, France.

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|September 25, 2016
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Summary
This summary is machine-generated.

Patients with chronic diseases want more information and shared decision-making during prescription renewal. They prefer the term "prescription revaluation" over "renewal" to better reflect their needs.

Keywords:
Choix du patientChronic diseaseDrug prescriptionsGeneral practiceMaladie chroniqueMédecine généraleOrdonnances médicamenteusesPatient preference

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Area of Science:

  • General Practice
  • Chronic Disease Management
  • Patient Preferences

Background:

  • Rising chronic disease incidence necessitates a focus on quality of care.
  • Prescription renewal was a primary reason for French outpatient visits in 2014.
  • Managing chronic diseases requires complex, long-term patient follow-up.

Purpose of the Study:

  • To explore patient preferences regarding prescription renewal.
  • To analyze how these preferences vary based on individual illness profiles.

Main Methods:

  • A self-administered questionnaire collected patient perceptions.
  • Data were gathered from adult patients across 14 French general practice offices.
  • The study was conducted between June and July 2014.

Main Results:

  • 307 questionnaires were returned within one month.
  • Over two-thirds of patients (69.7%) valued physician intervention highly.
  • 70% found prescription renewal essential or very important, prioritizing shared therapeutic options and disease information. Older patients sought more information on symptoms and disease.

Conclusions:

  • Patients actively engage in managing their chronic conditions.
  • Patients desire increased information and shared decision-making.
  • The term 'prescription revaluation' is preferred over 'renewal' to align with patient expectations.