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Spiradenoma causing longitudinal splitting of the nail
1Department of Dermatology, STD and Leprosy, All India Institute Of Medical Sciences, Patna, India. drabhijeetjha@gmail.com.
Clinical and Experimental Dermatology
|September 25, 2016
Summary
Eccrine spiradenoma, a rare skin tumor, can cause nail splitting. This case highlights its importance as a differential diagnosis for nail matrix growths, confirmed by histopathology.
Area of Science:
- Dermatopathology
- Oncology
Background:
- Longitudinal nail splitting can result from growths in the nail matrix.
- Differentiating between various nail matrix tumors is crucial for accurate diagnosis and treatment.
Observation:
- A 50-year-old woman presented with an 18-month history of longitudinal nail splitting and pain.
- Imaging revealed an intensely enhancing, hypervascular lesion suggestive of a glomus tumor.
- The lesion was tender to touch in the proximal nail fold region.
Findings:
- Histopathology revealed a well-circumscribed tumor with a dual cell population.
- The tumor stained negatively with periodic-acid-Schiff.
- The histopathological features were consistent with eccrine spiradenoma (ES).
Implications:
- Eccrine spiradenoma should be considered in the differential diagnosis of nail matrix tumors causing nail splitting.
- Accurate histopathological examination is essential for definitive diagnosis.
- This case expands the understanding of clinical presentations of eccrine spiradenoma.
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