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Probable metronidazole induced serum sickness-like reaction in a paediatric patient
H Z VanCleave1,2, A C Sanchez3,4, J A Lieberman1,2
1The University of Tennessee Health Science Center, Memphis, TN, USA.
What Is Known And Objective:
Metronidazole (MTZ) is a commonly prescribed antibiotic and is generally well tolerated. To our knowledge, there has been only one case report linking MTZ with serum sickness-like reaction (SSLR).
Case Summary:
We report a probable case of SSLR following the administration of MTZ in a paediatric patient.
What Is New And Conclusion:
Serum sickness-like reaction may be associated with MTZ therapy, and this type of adverse drug reaction may be underreported in the literature. A prior case report and evaluation with the Naranjo algorithm indicating a 'probable' adverse drug reaction provide evidence to support this conclusion.
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