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Effectiveness of cardiogoniometry compared with exercise-ECG test in diagnosing stable coronary artery disease in
I Zeljkovic1, H Pintaric1,2, M Vrsalovic1,3
1From the Department of Cardiology, Sisters of Charity University Hospital Centre, Vinogradska cesta 29, 10 000 Zagreb, Croatia.
Insights
Cardiogoniometry effectively diagnoses coronary artery disease (CAD) in women, outperforming the exercise-ECG test. This non-invasive method offers a promising alternative for screening women, particularly those unable to undergo stress testing.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Coronary artery disease (CAD) remains a significant health concern for women.
- Accurate and accessible diagnostic methods are crucial for early detection and management.
- Current diagnostic tools may have limitations in specific patient populations.
Purpose of the Study:
- To evaluate the diagnostic effectiveness of cardiogoniometry for CAD in women.
- To compare cardiogoniometry's performance against the exercise-ECG test.
- To establish coronary angiography as the reference standard for diagnosis.
Main Methods:
- A single-centre, case-series study involving 114 female patients with stable angina pectoris.
- Patients underwent cardiogoniometry and exercise-ECG testing prior to coronary angiography.
- Coronary angiography defined clinically significant CAD as >70% stenosis in one or more coronary lesions.
Main Results:
- Cardiogoniometry achieved 74.6% accuracy, with 75.0% sensitivity and 74.4% specificity for CAD detection.
- The exercise-ECG test showed lower accuracy (45.1%), sensitivity (68.1%), and specificity (36.6%).
- Cardiogoniometry demonstrated significantly higher accuracy (P < 0.001) and was associated with a nine-fold increased risk of CAD (OR 8.7).
Conclusions:
- Cardiogoniometry is a non-invasive, safe, and effective tool for diagnosing stable CAD in women.
- It exhibits superior diagnostic performance compared to the exercise-ECG test.
- Cardiogoniometry is suitable for primary care screening and for women unable to perform stress tests.
Aims:
To investigate the effectiveness of cardiogoniometry, a novel, non-invasive method, in diagnosing coronary artery disease (CAD) in women and compare it with exercise-ECG test, by using coronary angiography as a reference method.
Methods:
It was a single-centre, case-series study including consecutive female patients with stable angina pectoris (AP) undergoing coronary angiography. Exercise-ECG test, done according to the Bruce protocol, and cardiogoniometry were obtained prior to coronary angiography. Clinically significant CAD has been defined as one or more coronary lesions with >70% stenosis.
Results:
Study included 114 consecutive female patients with median age of 64.0 (58.0-71.0) years, out of which 32 (28.1%) had CAD. Cardiogoniometry yielded a total accuracy of 74.6% with a sensitivity of 75.0% (95% CI 56.6-88.5) and specificity of 74.4% (95% CI 63.6-83.4). Exercise-ECG test yielded a total accuracy of 45.1% with a sensitivity of 68.1% (95% CI 42.7-83.6) and specificity 36.6% (95% CI 25.2-50.3). Cardiogoniometry showed higher accuracy than exercise-ECG test ( P < 0.001). Pathological cardiogoniometry was associated with almost nine times higher risk for CAD (OR 8.7, 95%CI 3.4-22.3, P < 0.001), which remained significant after adjustment for age, and hypokinesia.
Conclusion:
Cardiogoniometry is a non-invasive, easy-to-use and free-of-risk method which showed high effectiveness in diagnosing stable CAD in women and superior to exercise-ECG test. Cardiogoniometry could be introduced as a part of the diagnostic algorithm of screening women for stable CAD and is suitable for use in the primary setting, especially in women unable to undergo stress-testing.
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