Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Development of Analytical Methods

Development of Analytical Methods

An analytical methodology can be divided into four sequential steps: technique, method, procedure, and protocol. A technique is a scientific principle that rationalizes a specific phenomenon through chemical measurements. Adapting a technique for analyzing a sample of interest is termed a method. The procedure outlines the directions for performing the analysis via an analytical method. The protocol is the detailed guidelines on the procedure, which should be strictly followed to obtain the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.

The AAPS journal·2022

Same author

Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma.

Journal of pharmaceutical and biomedical analysis·2022

Same author

Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance.

Drug metabolism and pharmacokinetics·2022

Same author

Toward highly sensitive and reproducible LC-MS/MS analysis of MK-8591 phosphorylated anabolites in human peripheral blood mononuclear cells.

Bioanalysis·2019

Same author

Strategy for peptide quantification using LC-MS in regulated bioanalysis: case study with a glucose-responsive insulin.

Bioanalysis·2018

Same author

Report on the 18th Annual Land O'Lakes Bioanalytical Conference.

Bioanalysis·2018

Search research articles

Related Experiment Video

Updated: Mar 14, 2026

Protease- and Acid-catalyzed Labeling Workflows Employing 18O-enriched Water

Protease- and Acid-catalyzed Labeling Workflows Employing 18O-enriched Water

Published on: February 20, 2013

Report on the 17th Annual Land O'Lakes Bioanalytical Conference.

Erik C Burns¹, Jeff Moran², Sheila Breidinger³

¹University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, USA.

|September 27, 2016

Summary

The 17th Annual Land O'Lakes Bioanalytical Conference focused on biomarker validation, stability, and regulatory issues. Experts shared insights on analyzing xenobiotics, metabolites, and biologics in biological matrices.

Keywords:

LC/MS technology analytical kits bioanalysis biomarkers biosimilars drug development flow cytometry microflow microsampling professional development regulatory guidance

More Related Videos

Immunoblot Analysis

Immunoblot Analysis

Published on: June 20, 2008

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

Published on: September 3, 2010

Related Experiment Videos

Last Updated: Mar 14, 2026

Protease- and Acid-catalyzed Labeling Workflows Employing 18O-enriched Water

Protease- and Acid-catalyzed Labeling Workflows Employing 18O-enriched Water

Published on: February 20, 2013

Immunoblot Analysis

Immunoblot Analysis

Published on: June 20, 2008

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

Published on: September 3, 2010

Area of Science:

Bioanalytical Chemistry
Pharmacology
Biomarker Analysis

Background:

The 17th Annual Land O'Lakes Bioanalytical Conference convened to address critical aspects of biomarker analysis.
The event focused on biomarker validation, stability, and regulatory considerations in bioanalytical science.

Framework:

The conference served as an educational forum for discussing the analysis of xenobiotics, metabolites, biologics, and biomarkers.
It encouraged an open exchange of scientific and methodological applications in bioanalysis.

Implementation:

The program featured a blend of lectures, interactive discussions, and a poster session to foster engagement.
The event was held from July 11-14, 2016, in Madison, WI, USA.

Implications:

The conference provided a platform for advancing best practices in bioanalytical method development and validation.
Discussions highlighted the importance of stability and regulatory compliance in biomarker research and application.