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Prostaglandin-induced hyperostosis. A case report

D M Drvaric1, W J Parks, J B Wyly

  • 1Emory University School of Medicine, Atlanta, Georgia 30303.

Clinical Orthopaedics and Related Research
|September 1, 1989
PubMed

Insights

Long-term prostaglandin-E1 (PGE1) infusions for congenital heart disease in infants can cause subperiosteal hyperostosis. This prostaglandin-induced bone reaction should be considered in neonatal cortical proliferation diagnoses.

Area of Science:

  • Neonatal medicine
  • Pediatric cardiology
  • Pediatric radiology

Background:

  • Prostaglandin-E1 (PGE1) is crucial for maintaining ductus arteriosus patency in infants with ductal-dependent congenital heart disease.
  • Long-term PGE1 therapy is a recognized treatment modality in this pediatric population.

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