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Related Concept Videos

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Stereotypes, Prejudice, and Discrimination02:55

Stereotypes, Prejudice, and Discrimination

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Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

312
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Related Experiment Video

Updated: Mar 14, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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Report reveals 'age restrictions' do exist.

Kate Williams

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |September 27, 2016
    PubMed
    Summary

    Elderly patients face discrimination within the National Health Service (NHS). A new report by the Royal College of Physicians highlights significant age-based disparities in care.

    Area of Science:

    • Geriatric Medicine
    • Healthcare Policy
    • Medical Ethics

    Background:

    • Growing concerns regarding ageism in healthcare.
    • The National Health Service (NHS) serves a large elderly population.
    • Previous anecdotal evidence suggested potential discrimination.

    Purpose of the Study:

    • To investigate allegations of discrimination against elderly patients by the NHS.
    • To provide evidence-based findings on age-related disparities in healthcare.
    • To inform policy changes for equitable patient care.

    Main Methods:

    • Analysis of a report published by the Royal College of Physicians.
    • Review of patient care data and physician testimonies.
    • Assessment of healthcare access and treatment protocols for elderly individuals.

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    Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
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    Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
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    Main Results:

    • The Royal College of Physicians report confirms discrimination against elderly patients.
    • Evidence indicates systemic age-based biases within the NHS.
    • Disparities were noted in treatment access and quality of care.

    Conclusions:

    • Elderly patients are subject to discrimination within the NHS.
    • Urgent policy reforms are needed to ensure equitable care for all age groups.
    • The findings necessitate a re-evaluation of healthcare practices regarding older adults.