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Updated: Mar 14, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
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Contraception for the perimenopausal woman.

A Linton1, A Golobof1, L P Shulman1,2

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Climacteric : the Journal of the International Menopause Society
|September 27, 2016
PubMed
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Women in perimenopause (menopause transition) can still get pregnant, facing higher risks. This review covers reproductive health issues and symptom management during this critical life stage.

Keywords:
Perimenopausecontraceptionmenopause transitionsymptom relief

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Area of Science:

  • Reproductive Endocrinology
  • Women's Health

Background:

  • Perimenopause marks a transition from reproductive years to menopause.
  • Women experience gynecological changes, new symptoms, and increased health risks.
  • Pregnancy risk persists during perimenopause, with elevated maternal morbidity and mortality.

Purpose of the Study:

  • To review reproductive issues during perimenopause.
  • To discuss interventions for pregnancy prevention and symptom relief.
  • To provide evidence for accurate reproductive counseling for women in menopause transition.

Main Methods:

  • Literature review of reproductive health in perimenopause.
  • Analysis of interventions for pregnancy prevention.
  • Examination of evidence for menopause symptom management.

Main Results:

  • Perimenopausal women remain fertile and face increased pregnancy complications.
  • Effective contraception and symptom management strategies are crucial.
  • Accurate, evidence-based counseling empowers informed health choices.

Conclusions:

  • Addressing reproductive health and pregnancy risks is vital during perimenopause.
  • Clinicians must offer comprehensive counseling on contraception and symptom management.
  • Optimizing care during the menopause transition improves women's long-term health outcomes.