Related Experiment Video
Updated: Mar 14, 2026
06:18
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
13.0K
Contraception for the perimenopausal woman
A Linton1, A Golobof1, L P Shulman1,2
1a Section of Family Planning, Department of Obstetrics and Gynecology of the Feinberg School of Medicine of Northwestern University , Chicago , Illinois , USA.
Climacteric : the Journal of the International Menopause Society
|September 27, 2016
Summary
Women in perimenopause (menopause transition) can still get pregnant, facing higher risks. This review covers reproductive health issues and symptom management during this critical life stage.
Area of Science:
- Reproductive Endocrinology
- Women's Health
Background:
- Perimenopause marks a transition from reproductive years to menopause.
- Women experience gynecological changes, new symptoms, and increased health risks.
- Pregnancy risk persists during perimenopause, with elevated maternal morbidity and mortality.
Purpose of the Study:
- To review reproductive issues during perimenopause.
- To discuss interventions for pregnancy prevention and symptom relief.
- To provide evidence for accurate reproductive counseling for women in menopause transition.
Main Methods:
- Literature review of reproductive health in perimenopause.
- Analysis of interventions for pregnancy prevention.
- Examination of evidence for menopause symptom management.
Main Results:
- Perimenopausal women remain fertile and face increased pregnancy complications.
- Effective contraception and symptom management strategies are crucial.
- Accurate, evidence-based counseling empowers informed health choices.
Conclusions:
- Addressing reproductive health and pregnancy risks is vital during perimenopause.
- Clinicians must offer comprehensive counseling on contraception and symptom management.
- Optimizing care during the menopause transition improves women's long-term health outcomes.
More Related Videos
Related Concept Videos
01:22Birth Control Methods
7.1K
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
7.1K
01:28Menopause
5.1K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
5.1K
01:21Intrauterine Drug Delivery Systems
100
Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
100
01:22Hormonal Regulation of the Menstrual Cycle
2.1K
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
2.1K
01:30Hormonal Control of the Ovarian Cycle
7.4K
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
7.4K
01:40Hormonal Regulation
49.4K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
49.4K