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Statistical methods for measuring interactions between protectors and sensitizers for freeze-thaw survival data
S R Chamberlin1, J Kruuv, D A Sprott
1Department of Statistics and Actuarial Science, University of Waterloo, Ontario, Canada.
Cryobiology
|August 1, 1989
Abstract:
A statistical model is developed to generate the survival probabilities of cells subjected to freeze-thaw treatments using various sensitizing and/or protective agents. The purpose is to determine whether different freeze-thaw protective agents act independently or whether there is an interaction between the agents. The model permits a statistical analysis of the data to yield an objective quantitative assessment of the size and nature of the interaction.