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Updated: Mar 14, 2026

Assessing Biofilm Dispersal in Murine Wounds
Published on: August 7, 2021
Postoperative washing of sutured wounds
Conrad Harrison1, Cian Wade2, Sinclair Gore3
1Medical Sciences Office, University of Oxford, UK.
Abstract:
A best evidence topic was written according to the structured protocol. The three part question addressed was: [In patients undergoing closure of surgical wounds with sutures] does [keeping the wound dry for the first 48 h after closure] [reduce the incidence of surgical site infections (SSIs)]? 4 relevant papers were culled from the literature and appraised. The authors, date, country, population, study type, main outcomes, key results and study weaknesses were tabulated. Current NICE guidelines recommend cleaning surgical wounds with sterile saline only for the first 48 h following skin closure. We found no evidence that washing wounds with tap water during this period increases the incidence of SSIs compared to keeping them dry. Further randomised controlled trials will enable the construction of conclusive systematic reviews and meta-analyses.
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