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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

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Unusual atypical language lateralization.

Muhammad T Khan¹, Roger Oghlakian¹, Mohamad Z Koubeissi¹

¹West Virginia University, Department of Neurology, 1 Medical Center Drive, Morgantown, WV 26506, United States.

Epilepsy & Behavior Case Reports

|September 27, 2016

Summary

This summary is machine-generated.

This case highlights the importance of thorough presurgical language assessment in epilepsy surgery planning. A right-handed woman with right-hemisphere abnormalities showed atypical language dominance, confirmed by Wada testing.

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Assessment of Cerebral Lateralization in Children using Functional Transcranial Doppler Ultrasound fTCD

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Published on: September 27, 2010

Area of Science:

Neuroscience
Neurosurgery
Epileptology

Background:

Determining language dominance is crucial for epilepsy surgery.
Atypical language representation can occur, especially with brain malformations.

Purpose of the Study:

To illustrate the necessity of comprehensive presurgical language assessment.
To present a unique case of atypical language lateralization in epilepsy.

Main Methods:

Case study of a 60-year-old right-handed female with epilepsy.
Utilized MRI, prolonged video-EEG monitoring, and functional MRI.
Confirmed language dominance using the Wada test.

Main Results:

Seizures localized to the right temporoparietal region.
Functional MRI was inconclusive for language lateralization.
Wada test strongly lateralized language to the right hemisphere.

Conclusions:

Thorough presurgical language evaluation is essential, especially in complex cases.
Atypical language representation can be present in individuals with congenital right-hemispheric malformations and epilepsy.
This case underscores the critical role of the Wada test in presurgical planning.