Pseudophakic cystoid macular edema: update 2016.
Andrzej Grzybowski1, Bartosz L Sikorski2, Francisco J Ascaso3
1Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland; Department of Ophthalmology, Poznań City Hospital, Poznań, Poland.
Clinical Interventions in Aging
|September 28, 2016
Summary
Pseudophakic cystoid macular edema (PCME) is a common cataract surgery complication. This review examines PCME causes, risk factors, and the use of anti-inflammatory drugs for prevention and treatment.
Area of Science:
- Ophthalmology
- Retinal diseases
- Ophthalmic surgery
Background:
- Pseudophakic cystoid macular edema (PCME) is the most frequent complication following cataract surgery.
- PCME can lead to decreased visual acuity, impacting patient outcomes.
- While inflammation is recognized as a contributor, the exact pathogenesis of PCME remains incompletely understood.
Approach:
- This paper provides an updated review of current research and clinical practices.
- It focuses on the pathogenesis and identified risk factors associated with PCME.
- The review critically examines the role of anti-inflammatory medications in PCME management.
Key Points:
- Steroids and nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly considered for PCME prophylaxis and treatment.
- A lack of standardized PCME definition and conflicting data on risk factors complicate research.
- Limited comparative studies exist on the efficacy of NSAIDs versus steroids in preventing PCME.
Conclusions:
- PCME remains a significant challenge in ophthalmology due to unresolved questions about its etiology and management.
- Further research is needed to clarify risk factors and compare the effectiveness of different anti-inflammatory agents.
- An improved understanding of PCME pathogenesis is crucial for optimizing post-cataract surgery care.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
01:28Angle Closure Glaucoma: Treatment
1.5K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.5K
01:25Glaucoma: Overview
1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K