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Updated: Mar 14, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Successful Intravascular Ultrasound-Guided Transradial Coronary Intervention with a 4Fr Guiding Catheter
Yasuhiro Nakano1, Kenji Sadamatsu2
1Department of Cardiovascular Medicine, Saga-Ken Medical Centre KOSEIKAN, Saga, Japan.
Insights
Smaller 4Fr guiding catheters reduce complications in coronary angiography. A new intravascular ultrasound (IVUS) system now enables IVUS-guided percutaneous coronary intervention (PCI) with these small catheters.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Minimizing catheter size in coronary angiography reduces vascular complications and contrast dye use.
- Historically, the small diameter of 4Fr guiding catheters limited the application of devices like intravascular ultrasound (IVUS).
Purpose of the Study:
- To demonstrate the feasibility of performing IVUS-guided percutaneous coronary intervention (PCI) using a 4Fr guiding catheter.
- To present a case study of successful IVUS-guided transradial PCI with a 4Fr guiding catheter.
Main Methods:
- Utilized a novel IVUS catheter system designed for use with a 0.010 guidewire.
- Performed transradial percutaneous coronary intervention (PCI) in a patient with silent myocardial ischemia.
- Employed a 4Fr guiding catheter for the procedure.
Main Results:
- Successfully performed IVUS-guided PCI using a 4Fr guiding catheter.
- The novel IVUS system and guidewire combination facilitated the use of advanced imaging in a smaller catheter profile.
- The procedure was completed in a 51-year-old male patient presenting with silent myocardial ischemia.
Conclusions:
- The combination of a novel IVUS catheter and a 0.010 guidewire enables IVUS-guided PCI with a 4Fr guiding catheter.
- This approach offers a potential strategy to minimize vascular access complications and contrast dye usage.
- This case highlights the advancement of interventional cardiology tools for minimally invasive procedures.
Abstract:
Minimizing the catheter size can reduce vascular access complications and contrast dye usage in coronary angiography. The small diameter of the 4Fr guiding catheter has limited the use of several angioplasty devices such as intravascular ultrasound (IVUS) in the past. However, the combination of a novel IVUS catheter and a 0.010 guidewire makes it possible to perform IVUS-guided percutaneous coronary intervention (PCI) with a 4Fr guiding catheter. We herein report the case of a 51-year-old man with silent myocardial ischemia who underwent IVUS-guided transradial PCI with a 4Fr guiding catheter.
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