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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
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Elective oocyte cryopreservation for deferred childbearing.
Kara N Goldman1, Jamie A Grifo
1New York University Fertility Center (NYUFC), NYU Langone Medical Center, New York, New York, USA.
Current Opinion in Endocrinology, Diabetes, and Obesity
|September 28, 2016
Summary
Elective oocyte cryopreservation allows women to defer childbearing, offering reproductive autonomy. Success rates for in-vitro fertilization (IVF) using cryopreserved eggs are comparable to fresh IVF cycles.
Area of Science:
- Reproductive Endocrinology
- Women's Health
- Fertility Preservation
Background:
- Delayed childbearing is a growing global trend, influenced by increased awareness of age-related fertility decline.
- Significant knowledge gaps exist among both patients and healthcare providers regarding the impact of maternal age on fertility and miscarriage risks.
Purpose of the Study:
- To review current trends in delayed childbearing.
- To summarize research on age-related fertility decline.
- To assess knowledge deficits concerning fertility and outcomes of elective oocyte cryopreservation.
Main Methods:
- Literature review of recent data on delayed childbearing.
- Analysis of studies on age-related fertility decline.
- Evaluation of outcomes following elective oocyte cryopreservation.
Main Results:
- Fertility declines and miscarriage rates increase with maternal age, yet women increasingly delay childbearing.
- Oocyte cryopreservation, while approved for medical indications, is increasingly used electively to defer childbearing.
- Elective oocyte cryopreservation demonstrates efficacy and safety, with live birth rates comparable to fresh in-vitro fertilization (IVF) cycles.
Conclusions:
- Oocyte cryopreservation offers a viable option for women seeking to defer childbearing and maintain reproductive autonomy.
- Success rates for in-vitro fertilization (IVF) using cryopreserved oocytes are equivalent to those using fresh oocytes.
- Enhanced patient and provider education on age-related fertility decline is crucial to mitigate unintended childlessness.
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