Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Geographic and Socioeconomic Variation in Aesthetic Plastic Surgery Pricing Across the United States: A State-Level Analysis of Income, Gross Domestic Product, and Real Economic Burden.

Aesthetic surgery journal. Open forum·2026
Same author

Evaluation of Aesthetic Outcomes Following Botulinum Toxin Treatment Using Multimodal Large Language Models: A Paired Before-and-After Analysis.

Aesthetic surgery journal. Open forum·2026
Same author

AI-based burn image assessment: Reliability and clinical error patterns of multimodal large language models in a repeated-inference study.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

AI in Dermato-Oncology: Diagnostic Performance and Prompt-Injection Vulnerability of Vision-Language Models in Dermoscopic Skin Cancer Assessment.

Cancers·2026
Same author

[Garbage In, Benchmark Out: A Case for the Courage to Publish Average Results].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...·2026
Same author

Artificial Intelligence in Medical Assessment: Reliability and Performance of Multimodal Large Language Models in a High-Stakes Licensing Examination.

Behavioral sciences (Basel, Switzerland)·2026

Related Experiment Video

Updated: Mar 14, 2026

Procedure for Decellularization of Porcine Heart by Retrograde Coronary Perfusion
11:30

Procedure for Decellularization of Porcine Heart by Retrograde Coronary Perfusion

Published on: December 6, 2012

24.6K

Flexor Tendon Sheath Engineering Using Decellularized Porcine Pericardium.

Kai Megerle1,2, Colin Woon1,2, Armin Kraus1,2

  • 1Palo Alto, Calif.

Plastic and Reconstructive Surgery
|September 28, 2016
PubMed
Summary
This summary is machine-generated.

Decellularized porcine pericardium shows promise as a scaffold for creating a functional tendon sheath. This tissue engineering approach could improve reconstructions where conventional methods are challenging.

More Related Videos

Procurement and Perfusion-Decellularization of Porcine Vascularized Flaps in a Customized Perfusion Bioreactor
10:56

Procurement and Perfusion-Decellularization of Porcine Vascularized Flaps in a Customized Perfusion Bioreactor

Published on: August 1, 2022

3.4K
Decellularization of Whole Human Heart Inside a Pressurized Pouch in an Inverted Orientation
06:28

Decellularization of Whole Human Heart Inside a Pressurized Pouch in an Inverted Orientation

Published on: November 26, 2018

11.9K

Related Experiment Videos

Last Updated: Mar 14, 2026

Procedure for Decellularization of Porcine Heart by Retrograde Coronary Perfusion
11:30

Procedure for Decellularization of Porcine Heart by Retrograde Coronary Perfusion

Published on: December 6, 2012

24.6K
Procurement and Perfusion-Decellularization of Porcine Vascularized Flaps in a Customized Perfusion Bioreactor
10:56

Procurement and Perfusion-Decellularization of Porcine Vascularized Flaps in a Customized Perfusion Bioreactor

Published on: August 1, 2022

3.4K
Decellularization of Whole Human Heart Inside a Pressurized Pouch in an Inverted Orientation
06:28

Decellularization of Whole Human Heart Inside a Pressurized Pouch in an Inverted Orientation

Published on: November 26, 2018

11.9K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Flexor tendon sheath reconstruction is challenging with current surgical techniques.
  • Tissue engineering offers a potential solution for complex reconstructive needs.

Purpose of the Study:

  • To evaluate decellularized porcine pericardium as a scaffold for engineering a biologically active human tendon sheath.

Main Methods:

  • Porcine pericardium was decellularized, preserving its structural and biochemical composition.
  • The scaffold was repopulated with human sheath synoviocytes and adipose-derived stem cells.
  • Cellular activity and matrix production were assessed over an 8-week period.

Main Results:

  • The engineered construct continuously produced hyaluronic acid, a key component of synovial fluid.
  • Adipose-derived stem cells exhibited altered collagen expression and increased hyaluronan synthase 2 activity.

Conclusions:

  • Decellularized porcine pericardium serves as a viable scaffold for developing a functional tendon sheath.
  • This biomaterial supports cellular activity crucial for creating a biologically active tissue engineered sheath.