Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cellular Differentiation

Cellular Differentiation

How does a complex organism such as a human develop from a single cell? It all starts from a single fertilized egg which gives rise to a vast array of cell types, such as nerve cells, muscle cells, and epithelial cells that characterize the adult? Throughout development and adulthood, cellular differentiation leads cells to assume their final morphology and physiology. Differentiation is the process by which unspecialized cells become specialized to carry out distinct functions.
A zygote is a...

Maturation of Endosomes

Maturation of Endosomes

The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB).
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...

Three Developmental Domains

Three Developmental Domains

Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...

Bacterial Protein Maturation

Bacterial Protein Maturation

Bacterial protein maturation is a tightly regulated process that ensures newly synthesized polypeptides achieve correct functional conformations. This maturation involves a series of modifications, folding events, and quality control steps, often assisted by specialized chaperone proteins.N-Terminal ModificationsThe maturation of bacterial polypeptides begins cotranslationally as the polypeptide exits the ribosome. The first amino acid, N-formylmethionine (fMet), is typically modified at the...

Introduction to Developmental Psychology

Introduction to Developmental Psychology

Developmental psychology explores the changes and continuities in human abilities throughout life, encompassing physical, cognitive, linguistic, and social dimensions. Human development is not restricted to growth, but includes aspects of decline, particularly in physical abilities as individuals age. Developmental psychologists seek to understand how people change as they age and how their mental and social skills evolve.Developmental MilestonesA key concept in developmental psychology is...

Zygotic Development And Stem Cell Formation

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Advancing cancer research via comparative oncology.

Nature reviews. Cancer·2025

Same author

Basement membrane patterning by spatial deployment of a secretion-regulating protease.

Proceedings of the National Academy of Sciences of the United States of America·2025

Same author

Paraneoplastic renal dysfunction in fly cancer models driven by inflammatory activation of stem cells.

Proceedings of the National Academy of Sciences of the United States of America·2024

Same author

Basement membrane patterning by spatial deployment of a secretion-regulating protease.

bioRxiv : the preprint server for biology·2024

Same author

Paraneoplastic renal dysfunction in fly cancer models driven by inflammatory activation of stem cells.

bioRxiv : the preprint server for biology·2024

Same author

Systemic coagulopathy promotes host lethality in a new Drosophila tumor model.

Current biology : CB·2023

Search research articles

Related Experiment Video

Updated: Mar 14, 2026

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

The Maturation of Development.

¹Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94708, USA.

Developmental Cell

|September 28, 2016

Summary

A broader definition of developmental biology is proposed to encompass new research into adult homeostasis and physiology. This expansion reflects the field's ongoing "Golden Age" of discovery.

Area of Science:

Developmental Biology
Physiology
Homeostasis

Background:

Current definitions of developmental biology may not fully encompass emerging research areas.
Studies investigating adult physiological processes are increasingly linked to developmental principles.

Purpose of the Study:

To propose an updated and expanded definition of developmental biology.
To highlight the integration of adult homeostasis and physiology research within the field.

Main Methods:

Literature review and synthesis of current research trends.
Analysis of the scope and boundaries of developmental biology.

Main Results:

The field of developmental biology is expanding beyond its traditional focus.

More Related Videos

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools

Published on: December 16, 2015

Analysis of the Development of a Morphological Phenotype as a Function of Protein Concentration in Budding Yeast

Analysis of the Development of a Morphological Phenotype as a Function of Protein Concentration in Budding Yeast

Published on: March 24, 2010

Related Experiment Videos

Last Updated: Mar 14, 2026

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools

Published on: December 16, 2015

Analysis of the Development of a Morphological Phenotype as a Function of Protein Concentration in Budding Yeast

Analysis of the Development of a Morphological Phenotype as a Function of Protein Concentration in Budding Yeast

Published on: March 24, 2010

Research into adult homeostasis and physiology represents a significant and growing area within developmental biology.

Conclusions:

An updated, broader definition is necessary to accurately represent the current scope of developmental biology.
Recognizing these expanded research directions will foster continued innovation and discovery in the field.