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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
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[Cutaneous leishmaniasis in a Syrian refugee]
M de Wild1, F H Wiersma, T F W Wolfs
1UMC Utrecht, Wilhelmina Kinderziekenhuis, Utrecht.
Nederlands Tijdschrift Voor Geneeskunde
|September 29, 2016
Summary
Cutaneous leishmaniasis, a rare disease in the Netherlands endemic to Syria, can appear years after exposure. Early diagnosis in Syrian refugees presenting with skin lesions is crucial for effective treatment and cosmetic outcomes.
Area of Science:
- Dermatology
- Infectious Diseases
- Public Health
Background:
- Cutaneous leishmaniasis is rare in the Netherlands but endemic in Syria.
- The disease has a potential for late manifestation years after initial exposure.
- Increased Syrian refugee migration necessitates heightened awareness of this condition.
Purpose of the Study:
- To highlight the importance of considering cutaneous leishmaniasis in Syrian refugees.
- To emphasize the diagnostic considerations for this rare condition in a non-endemic setting.
- To underscore the impact of timely treatment on long-term cosmetic results.
Main Methods:
- A case study of a 5-year-old Syrian boy presenting with hepatosplenomegaly.
- Incidental finding of a solitary, erythematous plaque on the cheek.
- Differential diagnosis including visceral leishmaniasis due to hepatosplenomegaly.
- Confirmation of cutaneous leishmaniasis through investigations.
Main Results:
- A 5-year-old Syrian refugee was diagnosed with cutaneous leishmaniasis.
- The patient presented with hepatosplenomegaly and a characteristic skin lesion.
- Diagnosis was confirmed despite the rarity of the disease in the Netherlands.
Conclusions:
- Cutaneous leishmaniasis should be considered in Syrian refugees with ulcerating nodules or plaques.
- Prompt local treatment can positively influence long-term cosmetic outcomes.
- Increased vigilance is necessary due to the rising incidence in Syria.

